019. PENTRAXIN-3 PLASMA LEVELS AND GENE POLYMORPHISMS IN ANCA-ASSOCIATED VASCULITIS
نویسندگان
چکیده
منابع مشابه
Detection of Anti-Pentraxin-3 Autoantibodies in ANCA-Associated Vasculitis
OBJECTIVES Pentraxin 3 (PTX3), in common with myeloperoxidase and proteinase 3, is stored in human neutrophil granules and is expressed on apoptotic neutrophil surface. We therefore investigated the presence of anti-PTX3 autoantibodies (aAbs) in the sera of antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) patients. METHODS Presence of anti-PTX3 autoantibodies was analy...
متن کاملUpdates in ANCA-associated vasculitis.
Antineutrophil cytoplasm antibody (ANCA)-associated vasculitides are small-vessel vasculitides that include granulomatosis with polyangiitis (formerly Wegener's granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome). Renal-limited ANCA-associated vasculitides can be considered the fourth entity. Despite their rarity and still unknow...
متن کاملTreatment of ANCA – Associated Vasculitis
ANCA – associated vasculitis (AAV) encompass Wegener granulomatosus (WG), Churg Strauss syndrome (CSS) and Microscopic Polyangiitis (MPA). Granuloma formation characterizes both WG and CSS, while necrotising inflammation of middle to small arteries, pauci-immune glomerulonephritis and production of ANCA typify all three of them. Common clinical and laboratory features point towards common patho...
متن کاملEpidemiology of ANCA associated vasculitis
ANCA associated vasculitis (AAV) comprises three syndromes with systemic vasculitis (Wegener’s granulomatosis (WG), Churg Strauss syndrome (CSS) and microscopic polyangiitis (MPA)), which all involve small and medium sized vessels and are associated with antibodies against cytoplasmatic antibodies in neutrophils (ANCA). Polyarteritis nodosa (PAN) is included in this review as it also affects me...
متن کاملANCA-associated small-vessel vasculitis.
Antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis is the most common primary systemic small-vessel vasculitis to occur in adults. Although the etiology is not always known, the incidence of vasculitis is increasing, and the diagnosis and management of patients may be challenging because of its relative infrequency, changing nomenclature, and variability of clinical expression. ...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2019
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/kez057.018